Posts Tagged ‘lucrin’

I did a long protocol IVF with lucrin and 12 out of 13 retrieved eggs were immature (matured in lab). I felt awful while taking the lucrin, blood pressure was high, dizzy and swollen ankles. 2 blasocysts (one hatching) were transferred, but resulted in negative. My FS has recommended the Cetrotide protocol for my next IVF. If this is a new protocol, why is long protocol and lucrin still the preference for one’s first IVF? What are the chances of mature eggs from cetrotide protocol if long protocol resulted in mostly immature eggs? Could the reason for so many immature eggs have been because lucrin had a negative effect on my body?

Sunday, November 9th, 2008

Cetrotide protocols are not new. It has been around for quite a few years now. About 65% of all cycles worldwide however, are still Lucrin cycles. This is probably due to the fact that Lucrin has been tried and tested for many years , having given good results for many years. The availability of Cetrotide has given us more options and the ability to change protocols where required.

There is no guarantee that the cetrotide will lead to a different outcome, but is worthwhile doing if indicated. It is unlikely that the reason for the immature eggs was the Lucrin – it could be that it was just a particular bad cohort of eggs or ovarian dysfunction

- Week 22 answers kindly provided by Dr. Stephan Volschenk -

Please ask a question regarding FET’s for me. If they are not going to do the transfer by co-ordinating it with ovulation but rather suppressing you with lucrin and using progynova to thicken the lining – should one continue with lucrin until you do a pregnancy test? At which stage is lucrin discontinued?

Wednesday, March 26th, 2008

The Lucrin is generally stopped on the day that the progesterone supplementation starts, which is 2 days before the embryo transfer is performed. However, this is one of the areas where we use the depot preparation in our clinic which means the Lucrin is already out of the system when the embryo transfer is done.

- Week 6 answers kindly provided by Dr. Stephan Volschenk -

What is the difference between the once off injection of Lucrin depot 3.75mg compared to the Lucrin patient pack daily injections?

Wednesday, March 26th, 2008

The difference between the 2 is in how it is used. Depot Lucrin is convenient from a patient point of view as it boils down to only one injection. The feeling is however that suppression of the ovary is too much, meaning that it takes longer and a bigger effort to recruit subsequent oocytes. For this reason we feel that the daily preparation is more suitable. However, the depot preparation does have a place in the treatment in so far as the preparation of uteri in donor egg and surrogate cycles where the degree of ovarian suppression is not that important.

- Week 6 answers kindly provided by Dr. Stephan Volschenk -

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