Archive for July, 2008

You mentioned that 60 days is the minimum period that should transpire between one IVF and the next, due to the fact that the ovaries need to recruit the next fresh cohort of antral follicles. Does this recruitment happen both on/off the BCP? Or does one need to be off the BCP for the 60 days? In other words, does down regualtion form part of this 60 day window or does down regulation still need to take place after the 60 day period? What is best practice and why? And also why do some clinics jump from one IVF to the next without the waiting period inbetween.

Monday, July 21st, 2008

60 – 90 days is an appropriate time frame. This is due to the following:

1)    It takes at least 6 – 8 weeks for the physiology to return back to normal.
2)    The ovary needs 60 – 70 days to recruit a new cohort of follicles.
3)    It takes a good 6 – 8 weeks to get over and work through the  emotional trauma of a failed cycle

Recruitment of primary oocytes in the ovary ( get the follicles to pre-antral stage) is a paracrine function of the ovary and is independent from FSH or LH hormones. It is therefore an ongoing process that is not influenced by external factors like the COC pill etc. I therefore have no idea why clinics “jump” from one cycle to the next.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

Please could you clarify what a chemical pregnacy is?

Monday, July 21st, 2008

A “chemical” pregnancy, or more commonly used term “biochemical” is when the embryo has implanted into the endometrium, but is too early to be detected on ultrasound and the only way the diagnosis can be made is by blood test.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

How soon after a chemical pregnancy detected at 4 weeks, and failing two days later, can one attempt another IVF cycle, and ideally, how soon after a failed IVF cycle can one attempt another one?

Monday, July 21st, 2008

The ideal time is 60 – 90 days.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

My husband has been diagnosed with varicocele, he is thinking about haveing the surgery to correct it. Are there any major risks associated with this type of surgery? Do the benifits outway the risks?

Monday, July 21st, 2008

It all depends on the grade of the varicocele, whether it is stage 1,2 or 3.
From a fertility perspective, varicocelectomy is only indicated under the following circumstances:
1)    The varicocele is clinically palpable
2)    The couple has known fertility
3)    The female partner has normal fertility or a potentially treatable cause for infertility
4)    The male partner has abnormal semen parameters

ALL of the above have to be present to justify surgery from a fertility perspective.
There are 2 ways of doing the procedure:
1)    Open surgery
2)    Embolization ( the preferred method)

Complications are bleeding, infection and cyctocele development.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

Hi Dr V. I need answers. My Dh has azoospermic testes. Both SAs n testicular biopsies confirmd this. He’s also bn taking these body building supplements called N1-natural testosterone which increases your endogenous testosterone levels 4 2yrs. He’s FSH,LH,PROLACTIN and TESTOS Levels are normal. He’s of indian decent n he’s parents are cousins. What is the cause of his infertility? Where can we find a good urologist specialising in infertility?

Monday, July 21st, 2008

In order to answer the question, I shall need more info, namely:
1)    The chromosomal analysis
2)    The result of the testicular biopsy
3)    The results of the clinical examination

We are not aware of urologists specializing in infertility as this is usually handled by an infertility unit.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

Could Dr V recommend any doctor or clinic in South Africa that can perform a microsurgical vasovasostomy or vaso-epididymostomy? If there are none in SA, which clinic’s in the UK or USA could he recommend?

Monday, July 21st, 2008

The best around is probably Silbermann in the USA. I shall get the contact details and post it  on the site.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

We have had 3 Full SA, always between 8- 10 million and morphology of 3-4. But the pre-spun Semen count is between 20 and 30 million everytime we do IUI. Will this be accurate? Can we say that the count has increased?

Monday, July 21st, 2008

The count has not increased. What you are looking at when it has been prepared for AI is a concentrated count.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

What is the chance of successful IUI if total count on Full SA was 10 Mil and 4% morphology and 55 % motility? Is it worth pursuing or should we move onto IVF immediately?

Monday, July 21st, 2008

Total count on full SA being 10 mil/ml is on the low side. One would therefore be inclined to move onto IVF/ICSI sooner rather than later.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

My mom, aunt and grandmother all suffered from uncontrollable bleeding (like a never-ending period) by the time they were in their late twenties, and all three had to have hysterectomies before they were 30. Luckily all three had had children by then (mom 3, gran 6 and aunt 4), but a hysterectomy at age 28 is scary. What could possibly cause this and could it be hereditary? I have an intense fear that it could happen to me too.

Monday, July 21st, 2008

There are numerous reasons for heavy menstrual bleeding – too many to mention here. The secret is to establish a firm diagnosis and then to treat accordingly.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

I have had 4 rounds of IUI. This last round I had slight cramps directly after IUI wich lasted for a couple of hours. I have never had these cramps with any previous IUI’s. What could the reason for cramping be? I found out today that there are 2 types of catheters used for IUI. A ‘thin’ one and a ‘soft’ one. What is the reason for two different types?

Monday, July 21st, 2008

Cramping post AI is not necessarily a bad sign. It is due to the presence of the sperm and media inside the uterus. A uterus always aims to be empty and therefore contracts in order to rid itself of anything on the inside but instead sucks the sperm into the fallopian tubes. It therefore varies from cycle to cycle and also might be due to a change in the media the sperm is prepared in.

With regards to the catheters: There are many types of insemination catheters. Some harder or softer than others. Which one is used usually depends on the clinician, in other words which he/she is comfortable in using.

- Week 18 answers kindly provided by Dr. Stephan Volschenk -

QUESTION?

You got a good question?
Ask it here >>

CATEGORIES


ARCHIVES