I came accross an article (http://acogjnl.highwire.org/cgi/content/abstract/86/6/917) where they refer to “normal uterine blood flow”. 1. I would like to know what this means,how you would test to see if it is a problem and what could be done if it turns out to be a problem. 2. The same article says the following: “In the clomiphene citrate-treated cycles, a statistically significant decrease in uterine blood flow also occurred during the early luteal phase (P < .05). ” Would this mean that there could be a problem with implantation? 3. Could the use of clomid affect the uterine blood flow once implantation has taken place, eg. week 7 of pregnancy?Sunday, June 1st, 2008
This refers to the blood flow in the uterus and more specifically to the endometrial lining. It is a very difficult parameter to evaluate and the best method is Doppler ultrasound measurements of the blood flow in the uterus and endometrium. This is not practical on a day to day basis and only of any value in a research setting. Clinically a thin endometrium may be an indication of sub optimal blood flow in that region and can be extremely difficult to manage. Studies using Viagra or exogenous estrogen supplementation were very disappointing and generally are of no value.
Clomiphene is a very potent anti estrogen and can have a negative impact on the lining and also the cervical mucus. This obviously can effect conception but should not have an effect on an established pregnancy.
- Week 15 answers kindly provided by Dr. Stephan Volschenk -